Dr. Abraham Teunissen, Icahn school of medicine, United States.
Dr. Abraham J. P. Teunissen ๐ is an Assistant Professor at the Biomedical Engineering and Imaging Institute, Icahn School of Medicine, New York ๐ฝ. He leads groundbreaking research in nanomedicine, radiochemistry, and immunotherapy ๐งฌ. With a Ph.D. in Molecular Engineering, he has authored high-impact studies and holds key patents. Dr. Teunissen mentors future scientists ๐จโ๐ฌ๐ฉโ๐ฌ and champions diversity and inclusion. His work on trained immunity and advanced imaging technologies is shaping the future of personalized medicine ๐.
Professional Profile
๐Early Academic Pursuitsย
Abraham J. P. Teunissen, Ph.D., embarked on his academic journey at Fontys University of Applied Science, earning a B.ASc in Organic Chemistry in 2011, where he developed supramolecular polymers for improved hemodialysis. He continued at Eindhoven University of Technology, securing an M.Sc. in Molecular Engineering (2013) and completing a Ph.D. (2017) focused on competing interactions in chemical reaction networks. His early research on biomimetic systems and chemical networks laid the foundation for a distinguished career in biomedical sciences.
๐ขProfessional Endeavorsย
Dr. Teunissenโs professional journey showcases a trajectory of growth and leadership. He held appointments at the prestigious Icahn School of Medicine at Mount Sinai, progressing from Postdoctoral Scientist (2017) to Instructor (2019), and ultimately to Assistant Professor (2022). He also serves as the Director of Radiochemistry at the Biomedical Engineering and Imaging Institute. Beyond academia, he consulted for Trained Therapeutix Discovery, driving translational innovation from 2019 to 2021.
๐ฌContributions and Research Focus On Immunologyย
Dr. Teunissen has made notable contributions to nanomedicine, immunology, and molecular imaging. His research lab develops novel nanotherapies and imaging probes to modulate and monitor the immune system in various diseases โ including cancer, cardiovascular disease, diabetes, and organ transplantation. His teamโs work spans small and large animal models, advancing therapeutic strategies with clinical relevance. His radiochemistry facility supports diverse collaborations, innovating nanoparticle tracking and immune monitoring using immuno-PET technology.
๐Impact and Influenceย
The outcomes of Dr. Teunissen’s research have wide-reaching impacts. His lab’s pioneering work on trained immunity modulation has driven forward collaborations, clinical translation efforts, and even the founding of a biotech company, Trained Therapeutix Discovery. His immuno-PET technologies enhance understanding of disease mechanisms and inform therapeutic interventions, demonstrating translational significance from bench to bedside.
๐Academic Cites and High-Impact Publicationsย
Dr. Teunissen’s work has appeared in leading journals such as Cell, Nature Biomedical Engineering, Nature Nanotechnology, and Science Translational Medicine. His high citation count reflects the significance of his research, especially in trained immunity, nanomedicine, and molecular imaging fields. These citations highlight his contributions to both fundamental science and applied biomedical research.
๐Awards and Honorsย
While specific individual awards were not detailed, Dr. Teunissen’s achievements include serving as an ad-hoc NIH and American Cancer Society grant reviewer, organizing major scientific symposia, and designing graduate-level coursework. His leadership roles โ like incident commander and scientific advisory organizer โ reflect high institutional trust and professional recognition.
๐ฎLegacy and Future Contributionsย
Dr. Teunissenโs legacy is rooted in scientific excellence, mentorship, and innovation. With an active lab mentoring a diverse group of postdocs, graduate, and premedical students, he is shaping the next generation of biomedical engineers and nanomedicine scientists. His future contributions are expected to further bridge fundamental science and clinical application, aiming to improve therapeutic outcomes for major diseases through immune modulation and advanced molecular imaging. His strong commitment to diversity, inclusion, and education ensures a lasting positive impact on both science and society.
๐Publications Top Notes
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Development of Methods for the Determination of pKa Values
๐ฐ Analytical Chemistry Insights | ๐ 483 citations | ๐
2013
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Investigating Supramolecular Systems Using Fรถrster Resonance Energy Transfer
๐ฐ Chemical Society Reviews | ๐ 159 citations | ๐
2018
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Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition
๐ฐ Cell | ๐ 145 citations | ๐
2020
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Efficacy and Safety Assessment of a TRAF6-Targeted Nanoimmunotherapy in Atherosclerotic Mice and Non-Human Primates
๐ฐ Nature Biomedical Engineering | ๐ 128 citations | ๐
2018
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End Groups of Functionalized Siloxane Oligomers Direct Block-Copolymeric or Liquid-Crystalline Self-Assembly Behavior
๐ฐ Journal of the American Chemical Society | ๐ 110 citations | ๐
2016
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Tumor Targeting by ฮฑvฮฒ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking
๐ฐ ACS Nano | ๐ 93 citations | ๐
2020
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Directing the SelfโAssembly Behaviour of PorphyrinโBased Supramolecular Systems
๐ฐ Chemistry โ A European Journal | ๐ 82 citations | ๐
2017
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Imaging-Assisted Nanoimmunotherapy for Atherosclerosis in Multiple Species
๐ฐ Science Translational Medicine | ๐ 68 citations | ๐
2019
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Prosaposin Mediates Inflammation in Atherosclerosis
๐ฐ Science Translational Medicine | ๐ 65 citations | ๐
2021
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Nuclear Imaging Approaches Facilitating Nanomedicine Translation
๐ฐ Advanced Drug Delivery Reviews | ๐ 63 citations | ๐
2020
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Probing Myeloid Cell Dynamics in Ischaemic Heart Disease by Nanotracer Hot-Spot Imaging
๐ฐ Nature Nanotechnology | ๐ 61 citations | ๐
2020
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Mechanically Induced Gelation of a Kinetically Trapped Supramolecular Polymer
๐ฐ Macromolecules | ๐ 52 citations | ๐
2014
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Imaging Cardiovascular and Lung Macrophages with the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs
๐ฐ Circulation: Cardiovascular Imaging | ๐ 44 citations | ๐
2020
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Resolving Sepsis-Induced Immunoparalysis via Trained Immunity by Targeting Interleukin-4 to Myeloid Cells
๐ฐ Nature Biomedical Engineering | ๐ 37 citations | ๐
2023
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A Modular Approach Toward Producing Nanotherapeutics Targeting the Innate Immune System
๐ฐ Science Advances | ๐ 35 citations | ๐
2021
- An Iterative Sparse Deconvolution Method for Simultaneous Multicolor 19FโMRI of Multiple Contrast Agents
๐ฐ Magnetic Resonance in Medicine | ๐ 30 citations | ๐
2020
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