He Sudan | Molecular Biology | Best Researcher Award

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Prof. Dr. He Sudan | Molecular Biology | Best Researcher Award

Prof. Dr. He Sudan | Suzhou Institute of Systems Medicine | China

Prof. Dr. Sudan He is a Professor and Deputy Director at the Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College. She earned her Ph.D. from Peking Union Medical College and trained under Prof. Xiaodong Wang. Renowned for her pioneering work on necroptosis and regulated cell death, she has published 46 SCI-indexed papers, received over 6,200 citations, holds three patents, and serves on multiple editorial boards, making her a highly influential researcher in her field.

Profiles

Scopus 
Orcid

Early Academic Pursuits

Dr. Sudan He began her academic journey with a strong foundation in biomedical sciences, earning her Ph.D. from Peking Union Medical College. She honed her expertise in cell biology and immunology during her postdoctoral training in the laboratory of Professor Xiaodong Wang at the National Institute of Biological Sciences, Beijing. These early academic experiences shaped her research trajectory in regulated cell death and provided her with advanced scientific training that later enabled her to establish an independent research group at Soochow University.

Professional Endeavors

Dr. He has held several significant academic and leadership roles throughout her career. After joining Soochow University as a faculty member, she later relocated to the Suzhou Institute of Systems Medicine, where she built a thriving research program. In recognition of her contributions, she was appointed Deputy Director of the institute in 2023. She has also engaged extensively with industry-sponsored projects and served in editorial positions for reputed journals, contributing to the advancement of scientific publishing in her field.

Contributions and Research Focus

Dr. He’s research focuses on molecular mechanisms of regulated cell death, particularly necroptosis. Her pioneering work identified the essential role of RIP3 (RIPK3) in necroptosis and discovered the TLR3/4–TRIF–RIP3 axis as a key pathway in cell death. She further uncovered the ICP6-RIPK3 interaction as a host defense mechanism against viral infections. Recently, her group revealed the role of the RIP1-RIP3 complex in GVHD-associated inflammation, which opened avenues for novel therapeutic strategies now being tested in clinical trials.

Impact and Influence

Dr. He’s work has had a profound impact on both basic and translational research in cell death biology. Her discoveries have been published in prestigious journals such as Cell, PNAS, Nature Communications, Blood, Leukemia, and the Journal of Cell Biology. Her publications have received over 6,218 citations, reflecting her influence within the global research community. She has also contributed to drug discovery projects, particularly the identification of necroptosis inhibitors, thereby bridging the gap between fundamental biology and clinical applications.

Research Skills

Dr. He has demonstrated exceptional research skills in dissecting molecular signaling pathways, utilizing advanced cell biology techniques, and translating findings into clinical applications. Her expertise spans genetic manipulation, cell death assays, molecular imaging, and therapeutic target validation. She is equally adept at collaborative research, having worked with international and national partners, and at leading multidisciplinary teams to achieve groundbreaking outcomes. Her ability to integrate basic science with translational goals underscores her versatility as a researcher.

Awards and Honors

Dr. He has been recognized as an Elsevier Highly Cited Chinese Researcher, a testament to her research excellence and influence. She has successfully secured multiple national and industry-funded projects with a combined funding of around 3 million RMB. She has also received acknowledgment through editorial board appointments for journals like Cell Death and Disease and Frontiers in Cell Death, reflecting the academic community’s trust in her expertise.

Legacy and Future Contributions

Dr. He’s legacy lies in her trailblazing discoveries in necroptosis research, which have shaped current understanding of regulated cell death and its role in disease pathogenesis. Moving forward, she aims to expand her research into therapeutic applications, particularly in autoimmune diseases, inflammation, and oncology. Her ongoing clinical collaborations and translational projects suggest a promising future where her discoveries will directly influence patient care and therapeutic innovations.

Publications Top Notes

Harnessing ZIKV NS2A RNA for alleviating acute hepatitis and cytokine release storm by targeting translation machinery

Hepatology, 2025

Authors: Sudan Dan He, et al.

Citations: 1

Anagrelide and idarubicin combination induces GSDME-mediated pyroptosis as a potential therapy for high-PDE3A acute myeloid leukemia

Leukemia, 2025

Authors: Sudan Dan He, et al.

Citations: 2

Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16

Journal of Cell Biology, 2023 (Open Access)

Authors: Sudan Dan He, et al.

Citations: 7

Synthesis and evaluation of dihydrofuro[2,3-b]pyridine derivatives as potent IRAK4 inhibitors

European Journal of Medicinal Chemistry, 2023

Authors: Sudan Dan He, et al.

Citations: 4

Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model

Bioorganic Chemistry, 2023

Authors: Sudan Dan He, et al.

Citations: 5

Conclusion

Dr. Sudan He is an accomplished researcher whose pioneering work on regulated cell death and necroptosis has significantly advanced biomedical science. With over 6,218 citations, 46 SCI publications, and recognition as an Elsevier Highly Cited Chinese Researcher, her contributions bridge fundamental discoveries and clinical applications. As a Professor and Deputy Director, she has demonstrated exceptional leadership, innovation, and collaboration. Her ongoing projects and translational research ensure she will continue to make lasting impacts on therapeutics and global health.

Yong Liu | Molecular Biology | Best Researcher Award

Published on by Best Achievements

Mr. Yong Liu | Molecular Biology | Best Researcher Award

Mr. Yong Liu, Southwest University, China.

🧑‍🔬 Mr. Yong Liu is a passionate Master’s student at Southwest University. 🏫 He focuses on Bombyx mori 🐛 and CRISPR/Cas9 gene editing 🧬. With a first-author publication in the International Journal of Biological Macromolecules, he explores how BmPriS influences silk gland growth. 📄 His strengths lie in data analysis 📊, methodology design 🔬, and scientific writing ✍️. As an emerging researcher, Yong Liu is committed to advancing genetic studies and contributing meaningfully to molecular science. 🌟

Profile

ORCID ID

🎓 Early Academic Pursuits

Mr. Yong Liu is currently a third-year postgraduate student at Southwest University, China, pursuing a Master’s degree in the field of Biological Sciences. His academic journey reflects a deep-rooted interest in molecular biology and insect genetics, particularly focusing on Bombyx mori, the domestic silkworm. His early academic endeavors laid a strong foundation in genetic engineering techniques, including CRISPR/Cas9, positioning him for impactful contributions to the field of entomological biotechnology.

💼Professional Endeavors

Though still in the academic phase of his career, Mr. Liu has already ventured into scientific publishing, a significant milestone for any early-career researcher. He authored a peer-reviewed article in the International Journal of Biological Macromolecules, examining the role of BmPriS in promoting silk gland growth. His professional development is driven by methodological rigor, analytical depth, and a commitment to original scientific inquiry.

🔬 Contributions and Research Focus On Molecular Biology

Mr. Liu’s primary research interests lie in the study of Bombyx mori (silkworm) and the use of CRISPR/Cas9 gene editing technology. His notable contribution, published in the International Journal of Biological Macromolecules, explores how BmPriS promotes silk gland growth by regulating endoreplication in silkworms. He played a critical role in writing, editing, and conducting investigations during the project, offering insights into the molecular mechanisms influencing silk production.

🌍 Impact and Influence

Despite being early in his career, Mr. Liu’s work has been recognized internationally, with his article being indexed in SCI/Scopus and accessible via Elsevier. His research contributes to the understanding of genetic regulation in insects, a field with implications for both biotechnology and agriculture.

🧠 Research Skills

Mr. Liu possesses a robust set of research competencies, including:

  • CRISPR/Cas9 genome editing

  • Molecular biology techniques

  • Data analysis and visualization

  • Scientific writing and review

  • Formal experimental design

His hands-on experience in data curation, methodology, and original drafting affirms his proficiency in managing and executing complex biological research.

🏅 Awards and Honors

Mr. Liu has applied for the Young Scientist Award, showcasing his ambition to be recognized for his early but significant contributions to the field. While formal accolades are yet to be listed, the quality of his publication and indexed citation indicates high potential for future honors.

🏛️ Legacy and Future Contributions

Mr. Liu’s current work on the genetic enhancement of silk glands is poised to contribute significantly to the fields of molecular entomology, agricultural biotechnology, and genetic engineering. As he advances his academic career, his application of CRISPR/Cas9 technologies could lead to innovations with both scientific and commercial relevance. His dedication to original research and data integrity suggests a promising trajectory in academia and beyond.

Publications Top Notes

  1. 🧬 BmPriS promotes silk gland growth by regulating endoreplication in silkworm
    📖 Journal: International Journal of Biological Macromolecules
    👨‍🔬 Authors: Yong Liu, Zhengyi Li, Lili Zhou, Wenyi Jia, Zichong Zhou, Ying Yang, Yue Sun, Ping Lin, Guanwang Shen, Qingsong Liu et al.
    🧵 Keywords: Silkworm 🐛, Silk gland development 🧪, Endoreplication 🔄

  1. 🧫 CRISPR/Cas9-Mediated Knockout of BmGDAP2 in the Silkworm, Bombyx mori: Extended Lifespan and Altered Gene Expression Impacting Developmental Pathways
    📖 Journal: Insects
    👨‍🔬 Authors: Chaojun Yuan, Zichong Zhou, Qifeng Guo, Ying Yang, Yue Sun, Yong Liu, Wenyi Jia, Shuoqi Fan, Jinxin Wu, Xiaoting Hua et al.
    🧬 Keywords: CRISPR/Cas9 🧫, Genetic modification 🧠, Developmental biology 📈, Bombyx mori 🐛