Prof. Dr. Kenji Arakawa | Biosynthesis | Best Researcher Award
Prof. Dr. Kenji Arakawa , Hiroshima University, Japan.
🧪 Dr. Kenji Arakawa is a Professor at the Graduate School of Integrated Sciences for Life, Hiroshima University. With a Ph.D. in Chemistry from Tokyo Institute of Technology, his research focuses on 🧬 natural product biosynthesis, microbial secondary metabolism, and genome mining. 📚 He has authored impactful publications and received prestigious honors, including the JSBBA Young Scientists Award 🏅. His work continues to advance bioorganic chemistry and microbiological research on a global scale. 🌍
Profile
🎓 Early Academic Pursuits
Prof. Dr. Kenji Arakawa began his scientific journey with a Bachelor’s degree in Chemistry from the Tokyo Institute of Technology in 1995, followed by a Master’s in 1997 and Ph.D. in 1999 from the same institution. His early academic pursuits were marked by a deep interest in organic and natural product chemistry, leading to advanced research on archaeal membrane lipids, already demonstrating innovation in the field of bio-organic chemistry.
💼 Professional Endeavors
After completing his Ph.D., Prof. Arakawa expanded his research horizons through a Postdoctoral Fellowship at the University of Washington (1999–2002). He then returned to Japan and joined Hiroshima University, gradually rising through the academic ranks—Assistant Professor (2002–2009), Associate Professor (2009–2024), and finally Professor (2024–present) at the Graduate School of Integrated Sciences for Life, Hiroshima University. His career trajectory showcases consistent excellence and commitment to academic leadership.
🔬 Contributions and Research Focus On Biosynthesis
Prof. Arakawa’s research centers on the biosynthesis of natural products, secondary metabolism regulation, and microbial morphological differentiation. He is especially renowned for exploring the metabolic potential of streptomycetes using diverse genome-mining strategies including transcriptional repressor inactivation, signaling molecule modulation, and genome-wide deletion techniques 🔍🧫. His findings have significantly contributed to new antibiotic discovery and the understanding of microbial regulatory systems.
🌍 Impact and Influence
Prof. Arakawa has made significant global contributions to natural product biosynthesis, especially in the realm of streptomycetes-derived antibiotics and archaeal lipid chemistry. His collaboration with international researchers and participation in high-impact publications has elevated the visibility of Japanese biotechnology research. As Vice President of the Society for Actinomycetes Japan (2022–2025), he continues to shape the future of microbial and biochemical research.
🧠 Research Skills
Prof. Arakawa is proficient in organic synthesis, biosynthetic pathway elucidation, genetic manipulation of actinomycetes, and analytical techniques including NMR, calorimetry, and EM imaging. He has demonstrated mastery in constructing macrocyclic lipids, regulatory networks in antibiotic production, and the bioengineering of microbial pathways.
🏅 Awards and Honors
Prof. Arakawa’s outstanding research has been recognized through several prestigious awards:
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🥇 Teshima Memorial Doctoral Dissertation Award (2001)
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🥈 Hamada Award, Society for Actinomycetes Japan (2009)
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🥉 JSBBA Award for Young Scientists (2013)
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🏅 Young Scientists Award, Japan Bioindustry Association (2016)
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🔬 NAGASE Science Technology Award (2016)
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🏆 Hiroshima University President Award (2016)
These accolades affirm his role as a leading scientist in microbial and biochemical research.
🌐 Social Memberships
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Japan Society for Bioscience, Biotechnology, and Agrochemistry
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The Society for Actinomycetes Japan – Vice President (2022–2025)
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The Society for Biotechnology, Japan
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Japan Bioindustry Association
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The Chemical Society of Japan
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American Chemical Society
🏛️ Legacy and Future Contributions
As a pioneer in actinomycete genomics and bioactive natural product research, Prof. Arakawa’s legacy lies in his multidisciplinary approach to tackling pressing biological questions. His mentorship, leadership in scientific societies, and development of genome-mining methodologies are cultivating a new generation of molecular scientists. With ongoing projects in secondary metabolism regulation and metabolite induction, his future work promises to unravel novel biochemical pathways and therapeutic compounds.
Publications Top Notes
🔬 Isolation, Biosynthetic Investigation, and Biological Evaluation of Maniwamycin G
Journal of Natural Products, 2022
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🧫 Three 4-Monosubstituted Butyrolactones from a Regulatory Gene Mutant of Streptomyces rochei 7434AN4
Journal of Bioscience and Bioengineering, 2022
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🧠 Chemoenzymatic Synthesis, Computational Investigation, and Antitumor Activity of Monocyclic Lankacidin Derivatives
Bioorganic & Medicinal Chemistry, 2022
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🧬 Discovery of a Polyamino Acid Antibiotic Solely Comprising l-β-Lysine
ACS Chemical Biology, 2021
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🧪 Overexpression of SRO_3163 Induces Cyclohexene-Containing Enamide Production
Bioscience, Biotechnology, and Biochemistry, 2021
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🌱 Production of Agrocinopine A in Transgenic Tobacco and Rhizosphere Effect
Molecular Plant-Microbe Interactions, 2021
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🧬 Substrate Specificity of Cytochrome P450 Monooxygenases in Lankamycin Biosynthesis
Bioscience, Biotechnology, and Biochemistry, 2021
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🧠 Functional Analysis of P450 Monooxygenase SrrO in Streptomyces rochei
Biomolecules, 2020
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🧫 Poly(4-vinylaniline) Colloids and Antimicrobial Activity
Colloids and Surfaces A, 2020
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🧬 SrrB as a Negative Regulator in Lankacidin and Lankamycin Production
Frontiers in Microbiology, 2020
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🧬 Genome Sequence of Streptomyces rochei with Linear Chromosome and Plasmids
Scientific Reports, 2019
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🧫 Size of Polystyrene and Its Antimicrobial Activity
Materials Today Communications, 2019
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🧪 PVA/Polymer Colloid Nanocomposite Hydrogel Preparation
Chemistry Letters, 2019
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🧠 Computational Prediction of Lankacidin C Binding to Tubulin
ACS Omega, 2019
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🧪 Quinoprotein Dehydrogenase in Final Lankacidin Oxidation Step
Journal of Bioscience and Bioengineering, 2018
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🧫 Signaling Molecule Pathway Manipulation in Streptomyces Genome Mining
Antonie van Leeuwenhoek, 2018
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🧫 Antimicrobial Activities of Low-MW Polymers via Emulsion Polymerization
European Polymer Journal, 2018
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🧪 Polymers from Cationic Initiators for Antimicrobial Activity
Chemistry Letters, 2018
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