Xin Huang | Medicine | Best Researcher Award

Prof. Xin Huang | Medicine | Best Researcher Award 

Prof. Xin Huang, Shanghai Jiaotong University School of Medicine Xinhua Hospital, China.

Professor Xin Huang 🧬 is a leading expert in reproductive medicine, specializing in PCOS molecular mechanisms. With over a decade of cutting-edge research, she has published in top journals and received numerous provincial and national awards 🏆. Her work bridges clinical practice and molecular biology, advancing embryo selection and fertility treatments 👩‍⚕️🧪. Professor Huang is also known for her strong interdisciplinary skills, securing multiple competitive research grants and contributing significantly to women’s health globally 🌍💡.

Profile

SCOPUS ID

🎓 Early Academic Pursuits

Prof. Xin Huang earned her Bachelor of Biology from Shandong University (1994–1998), followed by a Master’s in Biochemistry and Molecular Biology at Qingdao Agricultural University (2002–2005), and culminating in a PhD in the same field from Beijing Forestry University (2005–2008). These formative years provided her with a solid foundation in molecular techniques and research methodologies.

💼 Professional Endeavors

Teacher (1998–2002) — Educated high school students at No. 5 Middle School in Zibo, Shandong.

Embryologist (2008–2017) — Served at the Reproductive Medicine Centre, Yuhuangding Hospital, affiliated with Qingdao Medical University in Yantai.

Senior Embryologist & Professor (2017–present) — Leads embryology research and clinical efforts at the Department of Assisted Reproduction, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine.

🔬 Contributions and Research Focus On Medicine 

Since 2008, Professor Huang has focused on reproductive and endocrine disorders, notably polycystic ovary syndrome (PCOS). She pioneered the use of genome-wide microarrays to analyze gene expression in cumulus cells from PCOS patients, identifying key molecular pathways (e.g., Wnt, MAPK, calcium signaling) and biomarkers like LHCGR, TNIK, SOCS3, RUNX2, GPX3, PTX3. Her work extended into lncRNA and miRNA profiling, revealing regulatory molecules such as XLOC_011402 (PWRN2) and miR‑509‑3p that influence steroidogenesis and follicular microenvironment. She also explored follicular fluid metabolomics, using Raman spectroscopy to uncover metabolic signatures predictive of embryo quality and pregnancy outcomes

🌍 Impact and Influence

Professor Huang’s research offers key biomarkers for oocyte and embryo selection in IVF, especially for PCOS populations. Her findings have significantly advanced our understanding of oestradiol regulation, anovulation mechanisms, and the interplay between noncoding RNAs and metabolic pathways — shaping clinical strategies in assisted reproduction.

🧠 Research Skills

  • Embryology: IVF‑ET, ICSI, embryo & oocyte cryopreservation, PGD/PGS, FISH, assisted hatching, time‑lapse monitoring, spindle imaging, sperm viability assays.

  • Molecular Biology: Microarrays (cDNA, miRNA, lncRNA), gene cloning (RACE), vector design, protein assays (SDS‑PAGE, blots), qPCR, BiFC, yeast-two-hybrid, protein expression/purification, reporter assays, transformation techniques.

🏅 Awards and Honors

  • 2nd Prize, Yantai Sci/Tech Award (2014 & 2016)

  • 3rd Prize, Maternal & Child Health Award (2015 & 2017)

  • 2nd Prize, Shandong Medical Sci/Tech Award (2018)

  • 2nd Prize, Shandong Sci/Tech Progress Award (2019)
    These honors reflect sustained excellence in PCOS research and clinical translation.

🏛️ Legacy and Future Contributions

Professor Huang’s integrative approach—merging molecular biomarkers with clinical embryology—has already reshaped IVF strategies for PCOS patients. Her ongoing work in androgen-induced inflammasome activation (NLRP3 in microglia) and clinical metabolomic profiling promises to deepen understanding of PCOS-related comorbidities like depression and refine embryo selection methods. Her legacy is one of innovative translational research, fostering continued breakthroughs in reproductive endocrinology and assisted reproduction.

Publications Top Notes

  1. 📊 Frontiers in Cell and Developmental Biology (2021)
    Title: Raman spectrum of follicular fluid: a potential biomarker for oocyte developmental competence in PCOS
    Authors: Huang X#, Hong L#, Wu Y#, Chen M, Kong P, Ruan J, Teng X, Wei Z*

  2. 🧬 Aging (2020)
    Title: Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in PCOS
    Authors: Huang X#, Wu B#, Chen M#, Hong L, Kong P, Wei Z, Teng X*

  3. 🧪 European Journal of Obstetrics & Gynecology and Reproductive Biology (2020)
    Title: Systematic oxidative stress is not associated with live birth rate in young non-obese PCOS patients undergoing ART
    Authors: Chen M#, Huang X#, Liu Y, Lei S, Wu Y, Chen Z, Hong L, Teng X*

  4. 🧫 BMJ Open (2020)
    Title: Embryo incubation by time-lapse systems vs. conventional incubators in women with diminished ovarian reserve: protocol for RCT
    Authors: Chen M#, Wu Y#, Huang X#, et al.

  5. 🧠 Reproductive Biology and Endocrinology (2018)
    Title: lncRNA (PWRN2)-mediated ceRNA network in oocyte nuclear maturation in PCOS
    Authors: Huang X#, Pan J#, Wu B, Teng X

  6. 🧬 Reproduction (2016)
    Title: miRNA-509-3p promotes estradiol secretion by targeting MAP3K8 in cumulus cells of PCOS patients
    Authors: Huang X*, Liu C, Hao C, et al.

  7. 📚 Journal of Assisted Reproduction and Genetics (2016)
    Title: Aberrant expression of long noncoding RNAs in cumulus cells from PCOS patients
    Authors: Huang X*, Hao C*, Bao H, et al.

  8. 🧬 Reproduction (2013)
    Title: Transcriptional profiles of cumulus cells from MI and MII oocytes in PCOS patients
    Authors: Huang X, Hao C*, Shen X, et al.

  9. 🧬 Reproductive Biology and Endocrinology (2013)
    Title: RUNX2, GPX3, PTX3 gene expression in cumulus cells and embryo competence in PCOS
    Authors: Huang X, Hao C*, Shen X, et al.

  10. 🔥 Journal of Cellular and Molecular Medicine (2019)
    Title: S100‐A9 protein in exosomes from follicular fluid promotes inflammation via NF‐κB in PCOS
    Authors: Li H, Huang X, Chang X, et al.

  11. 🧠 Gynecological Endocrinology (2016)
    Title: GABAA receptor subunit expression in cumulus cells during oocyte maturation
    Authors: Dai H, Hao C*, Huang X, et al.

 

Aude PERUSSEAU-LAMBERT | Medicine | Best Researcher Award

Dr. Aude PERUSSEAU-LAMBERT | Medicine| Best Researcher Award

Dr. Aude PERUSSEAU-LAMBERT, NHS, United Kingdom.

Dr. Aude Pérusseau-Lambert is a dedicated plastic and reconstructive surgeon with extensive expertise in burns research, medical education, and surgical innovation. She holds an MD, an MSc in Burns, Plastics & Reconstructive Surgery, and a PGCert in Medical Education. With a passion for surgical excellence, research, and leadership, she has contributed to cutting-edge studies and medical education initiatives. Currently, she serves as a Burns Research Fellow at Mid and South Essex NHS Foundation Trust, committed to advancing patient care and surgical techniques. 🔎✨

Professional Profile

🎓 Education

Dr. Aude Pérusseau-Lambert has an extensive academic background in medicine and surgery. She earned her 🩺 Doctor of Medicine (MD) from Universitatea de Medicina si Farmacia “Iuliu Hatieganu”, Romania, with a thesis on “Off-Pump CABG: Advantages, Disadvantages, Results.” She pursued an 🔬 MSc in Burns, Plastics & Reconstructive Surgery at University College London, focusing on biomaterials and tissue engineering. Additionally, she holds a 📜 PGCert in Medical Education from Brighton and Sussex Medical School and 🏅 MRCS qualifications from the Royal College of Surgeons.

🔬Research Contributions On Medicine

Dr. Aude Pérusseau-Lambert has made significant contributions to surgical research, particularly in burns, plastic, and reconstructive surgery. Her work on preoperative CT imaging as a predictive tool for incisional hernia outcomes has been recognized with prestigious awards. She has actively participated in clinical trials, journal clubs, and multidisciplinary research initiatives to advance patient care. As a Burns Research Fellow, she leads and supervises studies, driving innovation and excellence in surgical techniques and patient outcomes. 💡📚

💼 Employment History

  • Junior Clinical Fellow – Guy’s and St Thomas’ NHS Foundation Trust, London (Jun 2023 – Feb 2024)
  • Core Surgical Training Year 2 & 1 – University Hospitals Plymouth NHS Trust
  • Resident Medical Officer – Nuffield Health Brighton Hospital (Aug 2018 – Jul 2019)
  • Foundation Year Junior Doctor – St Mary’s Hospital, Isle of Wight NHS Foundation Trust (2017 – 2018)

🏆 Awards & Prizes

  • PLASTA Prize – ASiT (March 2023)
  • Best Poster Presentation – AWR Europe 2017, Royal College of Physicians, London
  • Marjorie England Dissection Prize – Autumn Scientific Meeting (Aug 2019)

🧑‍🏫 Teaching & Educational Involvement

Aude has taught at numerous prestigious institutions, including Brighton and Sussex Medical School and St Mary’s Hospital, where she facilitated sessions on surgical techniques and trauma management. Her passion for education also extends to leadership roles in organizing workshops and symposia.

💪 Leadership & Management

  • Co-lead Organiser – RSM APRAS 2024
  • Burns Research Fellow – Leading and supervising research projects
  • Editorial & Library Representative – Royal Society of Medicine, Plastic Surgery Council

Conclusion

Dr. Aude Pérusseau-Lambert is a dedicated surgeon, researcher, and educator committed to excellence in plastic and reconstructive surgery. With a passion for innovation, leadership, and patient-centered care, she continuously strives to advance medical education and surgical techniques. Her journey reflects resilience, expertise, and a profound dedication to improving healthcare standards. 🚀🔬

📚Publication Top Notes

“Preoperative CT Imaging as a Tool to Predict Incisional Hernia Outcomes Following Abdominal Wall Reconstruction: A Retrospective Cohort Analysis” (November 2023)

Authors: Marvin Lucas Frommer, Ryan Faderani, Muholan Kanapathy, Shadi Ghali, Aude Pérusseau-Lambert:

“Targeted Chemodenervation of the Posterior Belly of Digastric Muscle for the Management of Jaw Discomfort in Facial Synkinesis” (June 2021)

Authors: Elena Pescarini, Daniel P. Butler, Aude Lambert, Ruben Yap Kannan

Citations: 5

“Infection of the Hip Joint by Serratia marcescens” (March 2021)

Authors: Aude Lambert, Joe Jan Gouda, Hilal Fareed

“The Effect of Nitrile Gloves on Temperature Perception During Hot Water Immersion” (January 2025)

Authors: David Cussons, Aude Perusseau-Lambert, Quentin Frew, David Barnes, Simon Myers, Peter Dziewulski