He Sudan | Molecular Biology | Best Researcher Award

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Prof. Dr. He Sudan | Molecular Biology | Best Researcher Award

Prof. Dr. He Sudan | Suzhou Institute of Systems Medicine | China

Prof. Dr. Sudan He is a Professor and Deputy Director at the Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College. She earned her Ph.D. from Peking Union Medical College and trained under Prof. Xiaodong Wang. Renowned for her pioneering work on necroptosis and regulated cell death, she has published 46 SCI-indexed papers, received over 6,200 citations, holds three patents, and serves on multiple editorial boards, making her a highly influential researcher in her field.

Profiles

Scopus 
Orcid

Early Academic Pursuits

Dr. Sudan He began her academic journey with a strong foundation in biomedical sciences, earning her Ph.D. from Peking Union Medical College. She honed her expertise in cell biology and immunology during her postdoctoral training in the laboratory of Professor Xiaodong Wang at the National Institute of Biological Sciences, Beijing. These early academic experiences shaped her research trajectory in regulated cell death and provided her with advanced scientific training that later enabled her to establish an independent research group at Soochow University.

Professional Endeavors

Dr. He has held several significant academic and leadership roles throughout her career. After joining Soochow University as a faculty member, she later relocated to the Suzhou Institute of Systems Medicine, where she built a thriving research program. In recognition of her contributions, she was appointed Deputy Director of the institute in 2023. She has also engaged extensively with industry-sponsored projects and served in editorial positions for reputed journals, contributing to the advancement of scientific publishing in her field.

Contributions and Research Focus

Dr. He’s research focuses on molecular mechanisms of regulated cell death, particularly necroptosis. Her pioneering work identified the essential role of RIP3 (RIPK3) in necroptosis and discovered the TLR3/4–TRIF–RIP3 axis as a key pathway in cell death. She further uncovered the ICP6-RIPK3 interaction as a host defense mechanism against viral infections. Recently, her group revealed the role of the RIP1-RIP3 complex in GVHD-associated inflammation, which opened avenues for novel therapeutic strategies now being tested in clinical trials.

Impact and Influence

Dr. He’s work has had a profound impact on both basic and translational research in cell death biology. Her discoveries have been published in prestigious journals such as Cell, PNAS, Nature Communications, Blood, Leukemia, and the Journal of Cell Biology. Her publications have received over 6,218 citations, reflecting her influence within the global research community. She has also contributed to drug discovery projects, particularly the identification of necroptosis inhibitors, thereby bridging the gap between fundamental biology and clinical applications.

Research Skills

Dr. He has demonstrated exceptional research skills in dissecting molecular signaling pathways, utilizing advanced cell biology techniques, and translating findings into clinical applications. Her expertise spans genetic manipulation, cell death assays, molecular imaging, and therapeutic target validation. She is equally adept at collaborative research, having worked with international and national partners, and at leading multidisciplinary teams to achieve groundbreaking outcomes. Her ability to integrate basic science with translational goals underscores her versatility as a researcher.

Awards and Honors

Dr. He has been recognized as an Elsevier Highly Cited Chinese Researcher, a testament to her research excellence and influence. She has successfully secured multiple national and industry-funded projects with a combined funding of around 3 million RMB. She has also received acknowledgment through editorial board appointments for journals like Cell Death and Disease and Frontiers in Cell Death, reflecting the academic community’s trust in her expertise.

Legacy and Future Contributions

Dr. He’s legacy lies in her trailblazing discoveries in necroptosis research, which have shaped current understanding of regulated cell death and its role in disease pathogenesis. Moving forward, she aims to expand her research into therapeutic applications, particularly in autoimmune diseases, inflammation, and oncology. Her ongoing clinical collaborations and translational projects suggest a promising future where her discoveries will directly influence patient care and therapeutic innovations.

Publications Top Notes

Harnessing ZIKV NS2A RNA for alleviating acute hepatitis and cytokine release storm by targeting translation machinery

Hepatology, 2025

Authors: Sudan Dan He, et al.

Citations: 1

Anagrelide and idarubicin combination induces GSDME-mediated pyroptosis as a potential therapy for high-PDE3A acute myeloid leukemia

Leukemia, 2025

Authors: Sudan Dan He, et al.

Citations: 2

Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16

Journal of Cell Biology, 2023 (Open Access)

Authors: Sudan Dan He, et al.

Citations: 7

Synthesis and evaluation of dihydrofuro[2,3-b]pyridine derivatives as potent IRAK4 inhibitors

European Journal of Medicinal Chemistry, 2023

Authors: Sudan Dan He, et al.

Citations: 4

Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model

Bioorganic Chemistry, 2023

Authors: Sudan Dan He, et al.

Citations: 5

Conclusion

Dr. Sudan He is an accomplished researcher whose pioneering work on regulated cell death and necroptosis has significantly advanced biomedical science. With over 6,218 citations, 46 SCI publications, and recognition as an Elsevier Highly Cited Chinese Researcher, her contributions bridge fundamental discoveries and clinical applications. As a Professor and Deputy Director, she has demonstrated exceptional leadership, innovation, and collaboration. Her ongoing projects and translational research ensure she will continue to make lasting impacts on therapeutics and global health.

Yong Liu | Molecular Biology | Best Researcher Award

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Mr. Yong Liu | Molecular Biology | Best Researcher Award

Mr. Yong Liu, Southwest University, China.

🧑‍🔬 Mr. Yong Liu is a passionate Master’s student at Southwest University. 🏫 He focuses on Bombyx mori 🐛 and CRISPR/Cas9 gene editing 🧬. With a first-author publication in the International Journal of Biological Macromolecules, he explores how BmPriS influences silk gland growth. 📄 His strengths lie in data analysis 📊, methodology design 🔬, and scientific writing ✍️. As an emerging researcher, Yong Liu is committed to advancing genetic studies and contributing meaningfully to molecular science. 🌟

Profile

ORCID ID

🎓 Early Academic Pursuits

Mr. Yong Liu is currently a third-year postgraduate student at Southwest University, China, pursuing a Master’s degree in the field of Biological Sciences. His academic journey reflects a deep-rooted interest in molecular biology and insect genetics, particularly focusing on Bombyx mori, the domestic silkworm. His early academic endeavors laid a strong foundation in genetic engineering techniques, including CRISPR/Cas9, positioning him for impactful contributions to the field of entomological biotechnology.

💼Professional Endeavors

Though still in the academic phase of his career, Mr. Liu has already ventured into scientific publishing, a significant milestone for any early-career researcher. He authored a peer-reviewed article in the International Journal of Biological Macromolecules, examining the role of BmPriS in promoting silk gland growth. His professional development is driven by methodological rigor, analytical depth, and a commitment to original scientific inquiry.

🔬 Contributions and Research Focus On Molecular Biology

Mr. Liu’s primary research interests lie in the study of Bombyx mori (silkworm) and the use of CRISPR/Cas9 gene editing technology. His notable contribution, published in the International Journal of Biological Macromolecules, explores how BmPriS promotes silk gland growth by regulating endoreplication in silkworms. He played a critical role in writing, editing, and conducting investigations during the project, offering insights into the molecular mechanisms influencing silk production.

🌍 Impact and Influence

Despite being early in his career, Mr. Liu’s work has been recognized internationally, with his article being indexed in SCI/Scopus and accessible via Elsevier. His research contributes to the understanding of genetic regulation in insects, a field with implications for both biotechnology and agriculture.

🧠 Research Skills

Mr. Liu possesses a robust set of research competencies, including:

  • CRISPR/Cas9 genome editing

  • Molecular biology techniques

  • Data analysis and visualization

  • Scientific writing and review

  • Formal experimental design

His hands-on experience in data curation, methodology, and original drafting affirms his proficiency in managing and executing complex biological research.

🏅 Awards and Honors

Mr. Liu has applied for the Young Scientist Award, showcasing his ambition to be recognized for his early but significant contributions to the field. While formal accolades are yet to be listed, the quality of his publication and indexed citation indicates high potential for future honors.

🏛️ Legacy and Future Contributions

Mr. Liu’s current work on the genetic enhancement of silk glands is poised to contribute significantly to the fields of molecular entomology, agricultural biotechnology, and genetic engineering. As he advances his academic career, his application of CRISPR/Cas9 technologies could lead to innovations with both scientific and commercial relevance. His dedication to original research and data integrity suggests a promising trajectory in academia and beyond.

Publications Top Notes

  1. 🧬 BmPriS promotes silk gland growth by regulating endoreplication in silkworm
    📖 Journal: International Journal of Biological Macromolecules
    👨‍🔬 Authors: Yong Liu, Zhengyi Li, Lili Zhou, Wenyi Jia, Zichong Zhou, Ying Yang, Yue Sun, Ping Lin, Guanwang Shen, Qingsong Liu et al.
    🧵 Keywords: Silkworm 🐛, Silk gland development 🧪, Endoreplication 🔄

  1. 🧫 CRISPR/Cas9-Mediated Knockout of BmGDAP2 in the Silkworm, Bombyx mori: Extended Lifespan and Altered Gene Expression Impacting Developmental Pathways
    📖 Journal: Insects
    👨‍🔬 Authors: Chaojun Yuan, Zichong Zhou, Qifeng Guo, Ying Yang, Yue Sun, Yong Liu, Wenyi Jia, Shuoqi Fan, Jinxin Wu, Xiaoting Hua et al.
    🧬 Keywords: CRISPR/Cas9 🧫, Genetic modification 🧠, Developmental biology 📈, Bombyx mori 🐛

Rui Wang | Molecular Biology | Best Researcher Award

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Mrs.  Rui Wang | Molecular Biology | Best Researcher Award

Mrs. Rui Wang, Beijing Children’s Hospital, China.

Rui Wang is a distinguished researcher specializing in environmental science and microbiology. With a Ph.D. in Environmental Engineering from the Chinese Academy of Sciences and a Master’s degree in Earth and Environmental Science from the University of Paul Cezanne, France, his academic journey is marked by excellence. His research focuses on antibiotics and heavy metals residue analysis, gut microbiota’s role in obesity, and antibiotic resistance genes. Dr. Wang has made significant contributions through projects addressing global challenges and has authored numerous impactful publications. His expertise in advanced analytical techniques further reinforces his role as a leader in his field.

Author Profile:

Scopus Profile

Summary of Suitability for Best Researcher Award:

Dr. Rui Wang  is highly suited for the Best Researcher Award due to his extensive and impactful research in environmental engineering, microbiology, and antibiotic resistance. His work, spanning multiple international projects, focuses on antibiotic and heavy metal residues in complex matrices and their effects on gut microbiota, with particular attention to obesity and antibiotic resistance. Rui’s diverse research experience includes leading projects funded by the National Natural Science Foundation of China and conducting influential studies on anaerobic digestion, wastewater treatment, and microbial community dynamics.

🎓 Education Background:

Dr. Rui Wang possesses an impressive educational background that forms the foundation of his research expertise. He earned his Ph.D. in Environmental Engineering from the prestigious Chinese Academy of Sciences, where his dissertation explored the effects of tetracyclines, copper, and their resistance genes on swine manure anaerobic digestion. Prior to this, he completed a Master’s degree in Earth and Environmental Science at the University of Paul Cezanne, France, focusing on arsenic uptake around rice roots in contaminated soils. Rui Wang began his academic journey with a Bachelor’s degree in Water Supply and Sewerage Engineering from Hebei University of Engineering, China.

💼 Professional Experience:

Dr. Rui Wang has extensive professional experience in environmental sciences and analytical chemistry. He served as a Postdoctoral Fellow in Biology at the Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, from 2015 to 2017. During this time, he conducted groundbreaking research on antibiotic resistance genes and their environmental impacts. Dr. Wang has also contributed significantly to water quality analysis through his role in projects such as the China-Sri Lanka Joint Center for Water Technology Research. Additionally, his expertise in advanced instrumentation, including HPLC-MS, ICP-MS, and GC-MS, has enabled him to develop innovative methods for analyzing complex environmental matrices.

🌍Research Contributions:

Dr. Rui Wang has made substantial contributions to environmental science, microbiology, and public health. His research addresses critical issues such as the analysis of antibiotic and heavy metal residues in complex matrices, the role of gut microbiota in obesity, and antibiotic resistance genes. Dr. Wang has led several impactful projects, including studies on the fate of antibiotics in swine manure anaerobic digestion and the effects of acetic acid on obesity-related intestinal microbes. His work on monitoring antibiotics in livestock and wastewater treatment systems has provided valuable insights into environmental health. With numerous publications, he continues to drive innovation in these fields.

🥇Award and Recognition

Dr. Rui Wang is a highly accomplished researcher whose work in environmental science and microbiology has made significant contributions to global health and environmental sustainability. Holding a Ph.D. in Environmental Engineering from the Chinese Academy of Sciences, his research focuses on critical areas such as antibiotics and heavy metals residue analysis, the gut microbiota’s role in obesity, and antibiotic resistance genes. With numerous impactful publications and international conference presentations, Dr. Wang’s expertise in advanced analytical techniques further solidifies his leadership in the field. His innovative approach and dedication to addressing pressing issues make him a deserving candidate for the Best Researcher Award.

Conclusion:

Dr. Rui Wang’s extensive academic background and pioneering research make him an ideal candidate for the Best Researcher Award. His work on antibiotics, heavy metals, and the gut microbiota’s role in obesity addresses pressing global health and environmental challenges. Dr. Wang’s leadership in innovative projects, combined with his proficiency in advanced analytical techniques, showcases his exceptional contributions to environmental science and microbiology. His numerous publications, international conference presentations, and commitment to advancing knowledge in his field demonstrate his lasting impact, making him a highly deserving candidate for this prestigious recognition.

📚Publication Top Notes

Simulating the multi-media fate of perfluorooctane sulfonate (PFOS) and its precursors in the Bohai coastal region of China

Year: 2024

Publication: Science of the Total Environment

🌊🔬

Vitamin D alleviates HFD-induced hepatic fibrosis by inhibiting DNMT1 to affect the TGFβ1/Smad3 pathway

Year: 2024

Publication: iScience

💊🧬

Generation of RAB4A homozygous knockout induced pluripotent stem cell (iPSC) line

Year: 2024

Publication: Stem Cell Research

🧫🔬

Emission estimation and health risk evaluation of aquaculture drugs commonly used in China

Year: 2024

Publication: Science of the Total Environment

Citations: 1

🐟💡

Imbalance of early-life vitamin D intake targets ROS-mediated crosstalk between mitochondrial dysfunction and differentiation potential of MSCs associated with later obesity

Year: 2024

Publication: Stem Cell Research and Therapy

Citations: 1

🧬💪

Interactions and Conflicts between Urbanization and Greenness: A Case Study from Nanjing, China

Year: 2024

Publication: Remote Sensing

🏙️🌳

Decreased vitamin D bio-availability with altered DNA methylation of its metabolism genes in association with the metabolic disorders among school-aged children with degree I, II, and III obesity

Year: 2024

Publication: Journal of Nutritional Biochemistry

🧬🍽️

Simulating behavior of perfluorooctane sulfonate (PFOS) in the mainstream of a river system with sluice regulations

Year: 2024

Publication: Chemosphere

Citations: 1

🌊⚙️

Paternal preconceptional supplementation of n-3 polyunsaturated fatty acids alleviates offspring nonalcoholic fatty liver disease in high-fat diet-induced obese mice

Year: 2024

Publication: Food Frontiers🍔💊

Biomagnification and health risks of perfluoroalkyl acids (PFAAs) in seafood from the Yangtze river estuary of China

Year: 2024

Publication: Environmental Pollution

🦑💧