Tzong-Shyuan Lee | Biomedicine | Best Researcher Award

Prof. Tzong-Shyuan Lee | Biomedicine | Best Researcher Award 

National Taiwan University | Taiwan

Dr. Tzong-Shyuan Lee, DVM, Ph.D., is a distinguished Professor in the Graduate Institute and Department of Physiology at the College of Medicine, National Taiwan University, Taipei, Taiwan. His extensive research focuses on the pathophysiology of age-related diseases, particularly cardiovascular and neurodegenerative disorders. Dr. Lee’s investigations integrate clinical reagents, nutritional compounds, and traditional herbal medicines through comprehensive in vitro and in vivo approaches to explore therapeutic interventions. His pioneering work has identified several molecular targets and elucidated key mechanistic pathways involved in cardiovascular dysfunction, fatty liver disease, chronic kidney disease, and Alzheimer’s disease. With an impressive scholarly record of 144 publications, 7,843 citations across 6,667 documents, and an h-index of 50, Dr. Lee’s contributions have significantly advanced biomedical research on vascular biology and aging. He has also demonstrated outstanding editorial leadership as Associate Editor for Frontiers in Physiology and Journal of Physiological Investigator, and as Academic Editor for Scientifica (Vascular Medicine Section), Exploration of Endocrine and Metabolic Diseases, and Aging Advances. His expertise is further reflected in his role as an invited reviewer for more than 185 scientific journals. Beyond his research and editorial activities, Dr. Lee has provided exemplary academic leadership as Director of the Department and Graduate Institute of Physiology and as Chairman of the Institutional Animal Care and Use Committee at National Taiwan University. His sustained research excellence, coupled with his leadership and service, underscores his status as a leading figure in cardiovascular and aging-related disease research.

Profile: Scopus | Orcid

Featured Publications 

Lee, T.-S., et al. (2025). Genetic deletion of TRPM8 channels restores microvascular function and mitigates chronic kidney disease progression. Free Radical Biology and Medicine.

Lee, T.-S., et al. (2025). Bromelain enhances nitric oxide bioavailability: Bradykinin's link to TRPV1/Ca²⁺/AMPK/autophagy signaling. Biomedicine and Pharmacotherapy.

Lee, T.-S., et al. (2025). Rac1 signaling mediates the protection of apigenin against hepatic lipid accumulation and insulin resistance. Biomedicine and Pharmacotherapy.

Lee, T.-S., et al. (2025). Bromelain prevents Alzheimer's disease progression by suppressing oxidative stress and upregulating apolipoprotein A1 in 5x familial Alzheimer's disease transgenic mice. Journal of Agriculture and Food Research.

Lee, T.-S., et al. (2025). HMGB1 regulates adipocyte lipolysis via caveolin-1 signaling: Implications for metabolic and cardiovascular diseases. International Journal of Molecular Sciences.

Wenjuan Mo | Biological Sciences | Best Researcher Award

Dr. Wenjuan Mo| Biological Sciences | Best Researcher Award 

Dr. Wenjuan Mo, Fudan University, China.

🔬Dr. Wenjuan Mo is an Assistant Researcher at Fudan University, specializing in theoretical physics and bioinformatics. Her research focuses on the molecular mechanisms of Kluyveromyces marxianus, aiming to enhance industrial protein production 🌱 and ethanol yield ⚗️. She combines genetic engineering and chromosomal rearrangements to develop high-performance yeasts for biotechnological applications. 📈

👨‍🎓Profile

🎓 Early Academic Pursuits

Wenjuan Mo embarked on her academic journey with a Bachelor’s degree in Physics from the University of Electronic Science and Technology of China. Her keen interest in the fusion of biology and computational sciences led her to pursue a Ph.D. in Theoretical Physics and Bioinformatics at Fudan University. This strong interdisciplinary foundation has played a pivotal role in shaping her scientific inquiry and methodology.

🧪 Professional Endeavors

Upon completing her Ph.D., Dr. Mo continued her research journey at Fudan University, where she took on roles as a Postdoctoral Researcher and later as an Assistant Researcher. Her consistent commitment to academic excellence has helped solidify her role as a leading figure in yeast molecular biology and synthetic biotechnology.

🔬 Contributions and Research Focus On Biological Sciences

Dr. Mo’s research primarily targets the molecular mechanisms of Kluyveromyces marxianus, a novel yeast with notable industrial value due to its rapid growth and ethanol production capacity. Her work explores innovative strategies to engineer this yeast for industrial protein production, focusing on enhancing recombinant protein expression under high-temperature conditions and optimizing yield via chromosomal rearrangements. Her findings contribute significantly to the fields of synthetic biology, industrial biotechnology, and bioenergy.

🌍 Impact and Influence

Her research has the potential to revolutionize bio-manufacturing systems, especially in the production of recombinant proteins and biofuels. By addressing challenges in high-yield and high-temperature fermentation, she has paved the way for more sustainable and cost-effective bioprocessing techniques.

🧠 Research Skills

Wenjuan Mo demonstrates strong interdisciplinary expertise, integrating theoretical modeling, molecular biology, and computational bioinformatics. She is proficient in genome editing, protein engineering, chromosomal manipulation, and high-throughput analysis—skills critical to the success of industrial biotech applications. Her ability to bridge theory and practice makes her a valuable asset to any scientific team.

🏅 Awards and Honors

While specific awards were not listed, Wenjuan Mo’s progression through competitive academic positions and her sustained research contributions at a prestigious institution like Fudan University reflect her standing and recognition within the academic field.

🔮 Legacy and Future Contributions

Dr. Mo’s research trajectory suggests a promising future in genetic engineering, synthetic biology, and bio-production optimization. Her innovative work on Kluyveromyces marxianus not only enhances our understanding of non-conventional yeasts but also positions her as a leader in developing next-generation biotechnological applications. She is poised to continue making meaningful contributions to sustainable industrial practices and scientific innovation.

Publications Top Notes