University of Tokyo Hospital | Japan
Dr. Dehua Chang, M.D., Ph.D., is a highly accomplished researcher and clinician specializing in cardiovascular surgery and regenerative medicine. He currently serves as a Specially Appointed Associate Professor at the Department of Cell Therapy in Regenerative Medicine, University of Tokyo Hospital, and holds multiple visiting professorships at leading institutions, including Fudan University, Shanghai Jiao Tong University, and Zhengzhou University. With a prolific academic and professional background spanning Japan, China, Europe, and the United States, Dr. Chang has made significant contributions to stem cell therapy, tissue engineering, and cardiac regeneration. His work has been widely recognized, with 29 published documents, 838 citations, and an h-index of 15, reflecting his influential research impact in the field. He has developed several innovative patents related to cell sheet technologies and mesenchymal stem cell applications, advancing translational approaches in regenerative medicine. As a member of the Japanese Society for Regenerative Medicine and a reviewer for leading journals such as Stem Cell Research & Therapy, Regenerative Therapy, and Acta Biomaterialia, Dr. Chang contributes extensively to scientific peer review and editorial excellence. His clinical and research expertise encompasses cell-based therapies for ischemic heart disease, heart failure, osteoarthritis, and vascular disorders, with a focus on the industrialization and clinical application of stem cell sheet products. Fluent in Chinese, English, and Japanese, Dr. Chang bridges international collaboration, academic leadership, and innovation in regenerative cardiovascular medicine, positioning him as a global expert in translational medical research and clinical cell therapy.
Profile: Scopus
Featured Publications
Wang, Y.-H., Liu, T.-T., Guo, Y.-P., Zhu, S.-J., Liao, Z.-M., Song, J.-M., Zhu, X.-M., Liang, J.-L., Nasser, M. I., Liu, N.-B., Chang, D.-H., Zhu, P., & Yao, B.* (2025). Integrating melt electrospinning writing and microfluidics to engineer a human cardiac microenvironment for high-fidelity drug screening. Bioactive Materials.
Zhu, S., Xuan, J., Shentu, Y., Kida, K., Kobayashi, M., Wang, W., Ono, M., & Chang, D.* (2024). Effect of chitin-architected spatiotemporal three-dimensional culture microenvironments on human umbilical cord-derived mesenchymal stem cells. Bioactive Materials