Dehua Chang | Regenerative Medicine Research | Best Researcher Award

Published on by Best Achievements

Dr. Dehua Chang | Regenerative Medicine Research | Best Researcher Award 

University of Tokyo Hospital | Japan

Dr. Dehua Chang, M.D., Ph.D., is a highly accomplished researcher and clinician specializing in cardiovascular surgery and regenerative medicine. He currently serves as a Specially Appointed Associate Professor at the Department of Cell Therapy in Regenerative Medicine, University of Tokyo Hospital, and holds multiple visiting professorships at leading institutions, including Fudan University, Shanghai Jiao Tong University, and Zhengzhou University. With a prolific academic and professional background spanning Japan, China, Europe, and the United States, Dr. Chang has made significant contributions to stem cell therapy, tissue engineering, and cardiac regeneration. His work has been widely recognized, with 29 published documents, 838 citations, and an h-index of 15, reflecting his influential research impact in the field. He has developed several innovative patents related to cell sheet technologies and mesenchymal stem cell applications, advancing translational approaches in regenerative medicine. As a member of the Japanese Society for Regenerative Medicine and a reviewer for leading journals such as Stem Cell Research & Therapy, Regenerative Therapy, and Acta Biomaterialia, Dr. Chang contributes extensively to scientific peer review and editorial excellence. His clinical and research expertise encompasses cell-based therapies for ischemic heart disease, heart failure, osteoarthritis, and vascular disorders, with a focus on the industrialization and clinical application of stem cell sheet products. Fluent in Chinese, English, and Japanese, Dr. Chang bridges international collaboration, academic leadership, and innovation in regenerative cardiovascular medicine, positioning him as a global expert in translational medical research and clinical cell therapy.

Profile: Scopus 

Featured Publications 

Wang, Y.-H., Liu, T.-T., Guo, Y.-P., Zhu, S.-J., Liao, Z.-M., Song, J.-M., Zhu, X.-M., Liang, J.-L., Nasser, M. I., Liu, N.-B., Chang, D.-H., Zhu, P., & Yao, B.* (2025). Integrating melt electrospinning writing and microfluidics to engineer a human cardiac microenvironment for high-fidelity drug screening. Bioactive Materials.

Zhu, S., Xuan, J., Shentu, Y., Kida, K., Kobayashi, M., Wang, W., Ono, M., & Chang, D.* (2024). Effect of chitin-architected spatiotemporal three-dimensional culture microenvironments on human umbilical cord-derived mesenchymal stem cells. Bioactive Materials

ZhongChao Han | Stem cells |  Best Researcher Award

Published on by Best Achievements

Prof. ZhongChao Han | Stem cells |  Best Researcher Award 

National Engineering Research Center of Cell Products | China 

Dr. Zhong Chao Han is a distinguished Chinese hematologist and stem cell researcher, renowned for his pioneering work in mesenchymal stem cell (MSC) biology and regenerative medicine. He earned his Doctor of Medicine degree from Jiangxi Medical College and completed his Ph.D. in Life Sciences at the University of Occidental Bretagne in France. Dr. Han has held prominent academic and leadership positions, including professorships at Paris University VII and the Chinese Academy of Medical Sciences & Peking Union Medical College, where he also served as President of the Institute of Hematology & Hospital of Blood Diseases. His research has significantly advanced the field of MSCs, particularly in the context of perinatal tissues such as umbilical cord and placenta. Dr. Han's work has led to the development of clinical-grade MSC banks and innovative therapeutic applications, impacting thousands of patients. He has authored numerous influential publications, contributing to the understanding and clinical application of stem cell therapies. Dr. Han is a member of several prestigious scientific societies, including the World Federation of Hemophilia and the American Society of Hematology. His contributions continue to shape the landscape of stem cell research and its clinical applications.

Profile: Scopus 

Author, A. A., Author, B. B., & Author, C. C. (2020). A nitric oxide-releasing hydrogel for enhancing the therapeutic effects of mesenchymal stem cell therapy for hindlimb ischemia. Acta Biomaterialia.

Author, A. A., Author, B. B., & Author, C. C. (2020). High-efficient generation of VCAM-1+ mesenchymal stem cells with multidimensional superiorities in signatures and efficacy on aplastic anaemia mice. Cell Proliferation.

Author, A. A., Author, B. B., & Author, C. C. (2020). Twist1 promotes dendritic cell-mediated antitumor immunity. Experimental Cell Research.

Author, A. A., Author, B. B., & Author, C. C. (2020). Efficacy and safety of umbilical cord mesenchymal stem cells in treatment of cesarean section skin scars: A randomized clinical trial. Stem Cell Research and Therapy.

Author, A. A., Author, B. B., & Author, C. C. (2020). Enhanced therapeutic effects of MSC-derived extracellular vesicles with an injectable collagen matrix for experimental acute kidney injury treatment. Stem Cell Research and Therapy.