Tzong-Shyuan Lee | Biomedicine | Best Researcher Award

Prof. Tzong-Shyuan Lee | Biomedicine | Best Researcher Award 

National Taiwan University | Taiwan

Dr. Tzong-Shyuan Lee, DVM, Ph.D., is a distinguished Professor in the Graduate Institute and Department of Physiology at the College of Medicine, National Taiwan University, Taipei, Taiwan. His extensive research focuses on the pathophysiology of age-related diseases, particularly cardiovascular and neurodegenerative disorders. Dr. Lee’s investigations integrate clinical reagents, nutritional compounds, and traditional herbal medicines through comprehensive in vitro and in vivo approaches to explore therapeutic interventions. His pioneering work has identified several molecular targets and elucidated key mechanistic pathways involved in cardiovascular dysfunction, fatty liver disease, chronic kidney disease, and Alzheimer’s disease. With an impressive scholarly record of 144 publications, 7,843 citations across 6,667 documents, and an h-index of 50, Dr. Lee’s contributions have significantly advanced biomedical research on vascular biology and aging. He has also demonstrated outstanding editorial leadership as Associate Editor for Frontiers in Physiology and Journal of Physiological Investigator, and as Academic Editor for Scientifica (Vascular Medicine Section), Exploration of Endocrine and Metabolic Diseases, and Aging Advances. His expertise is further reflected in his role as an invited reviewer for more than 185 scientific journals. Beyond his research and editorial activities, Dr. Lee has provided exemplary academic leadership as Director of the Department and Graduate Institute of Physiology and as Chairman of the Institutional Animal Care and Use Committee at National Taiwan University. His sustained research excellence, coupled with his leadership and service, underscores his status as a leading figure in cardiovascular and aging-related disease research.

Profile: Scopus | Orcid

Featured Publications 

Lee, T.-S., et al. (2025). Genetic deletion of TRPM8 channels restores microvascular function and mitigates chronic kidney disease progression. Free Radical Biology and Medicine.

Lee, T.-S., et al. (2025). Bromelain enhances nitric oxide bioavailability: Bradykinin's link to TRPV1/Ca²⁺/AMPK/autophagy signaling. Biomedicine and Pharmacotherapy.

Lee, T.-S., et al. (2025). Rac1 signaling mediates the protection of apigenin against hepatic lipid accumulation and insulin resistance. Biomedicine and Pharmacotherapy.

Lee, T.-S., et al. (2025). Bromelain prevents Alzheimer's disease progression by suppressing oxidative stress and upregulating apolipoprotein A1 in 5x familial Alzheimer's disease transgenic mice. Journal of Agriculture and Food Research.

Lee, T.-S., et al. (2025). HMGB1 regulates adipocyte lipolysis via caveolin-1 signaling: Implications for metabolic and cardiovascular diseases. International Journal of Molecular Sciences.

Kalpana Mandal | Biosensors | Best Researcher Award

Dr. Kalpana Mandal | Biosensors | Best Researcher Award 

Terasaki Institute for Biomedical Innovations | United States

Dr. Kalpana Mandal is an accomplished biophysicist and biomedical engineer specializing in cell mechanics, biomaterials, tissue engineering, microfluidics, and organ-on-a-chip technologies. She earned her Ph.D. in Physics for Life Sciences from Grenoble University, France, following her M.Sc. in Physics from IIT Kanpur, India. Currently an Affiliate Researcher at the Terasaki Institute for Biomedical Innovation and Principal Scientist at KyberX LLC, she has previously contributed to advanced cellular engineering projects at Pandorum Technologies and biomaterial research at the University of Pennsylvania under Prof. Paul A. Janmey. Dr. Mandal’s research excellence is reflected in her over 46 scientific publications, 1,481 citations, and an h-index of 22. Her pioneering studies on mechanotransduction and engineered microenvironments have advanced understanding of disease modeling and regenerative medicine. She has been recognized with numerous accolades, including the Young Investigator Award (BMES) and the Rising Star in Bioengineering and Health Awards from Princeton, Columbia, and Johns Hopkins Universities. Beyond research, Dr. Mandal actively mentors emerging scientists, serves as a review editor for Frontiers in Cellular and Developmental Biology, and contributes to outreach initiatives fostering STEM engagement and diversity in biomedical research.

Profile: Scopus | Orcid

Featured Publications 

Nguyen, H. T., Tirpakova, Z., Peirsman, A., Maity, S., Falcone, N., Kawakita, S., Jeon, K., Khorsandi, D., Rashad, A., Farhadi, N., & Mandal, K. (2025). Embolization-on-a-chip: Novel vascularized liver tumor model for evaluation of cellular and cytokine response to embolic agents. Biofabrication.

Haghniaz, R., Aninwene, G. II, Zarei, F., Yiu, F., Mirmashhouri, B., Ramirez, J., Darabi, A., Tebon, P., Montazerian, H., & Mandal, K., et al. (2025, April). Biodegradable, flexible adhesive patch for urinary bladder suture line reinforcement. Applied Materials Today.

Raheem, A., Mandal, K., Biswas, S., Ahari, A., Najafabadi, A. H., Farhadi, N., Zehtabi, F., Gangrade, A., Mecwan, M., Maity, S., et al. (2025, March 1). Smart biomaterials in healthcare: Breakthroughs in tissue engineering, immunomodulation, patient-specific therapies, and biosensor applications. Applied Physics Reviews.